Ubiquitin mouse Monoclonal Antibody(5F1)

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601621

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商品描述
  • 靶点-Target

    Ubiquitin

  • 反应性

    Human,Rat,Mouse,Pig

  • 应用

    WB,IF,IHC

  • 宿主物种-Host Species

    Mouse

  • 修饰-Modification

    Unmodified

  • 推荐稀释比

    WB 1:1000-2000;IHC 1:100-200;IF 1:200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Monoclonal

  • 克隆号

    5F1

  • 免疫原

    Synthetic Peptide of Ubiquitin

  • 特异性

    Ubiquitin protein detects endogenous levels of Ubiquitin

  • 蛋白名称

    Ubiquitin

  • Organism-1

    Human

  • 基因ID-1

    7314

  • SwissProt-1

    P62979;P62987;P62988

  • 背景

    UBB (ubiquitin B) encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. UBB consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of UBB are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.