FGF-2 Polyclonal Antibody
¥680.00
PPAR Delta mouse Monoclonal Antibody(2F9)
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601610
- 产品信息
商品描述
靶点-Target
PPAR Delta
反应性
Human,Rat,Mouse
应用
IF,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
IF 1:50-200;IHC 1:100-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
2F9
免疫原
Recombinant Protein of PPAR Delta of PPAR Delta
特异性
PPAR Delta protein detects endogenous levels of PPAR Delta
基因名称
PPARD NR1C2 PPARB
蛋白名称
PPAR Delta
别名
Peroxisome proliferator-activated receptor delta;PPAR-delta;NUCI;Nuclear hormone receptor 1;NUC1;Nuclear receptor subfamily 1 group C member 2;Peroxisome proliferator-activated receptor beta;PPAR-beta;
Organism-1
Human
基因ID-1
5467
SwissProt-1
Q03181
Organism-2
Mouse
SwissProt-2
P35396
背景
peroxisome proliferator activated receptor delta(PPARD) Homo sapiens This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this
细胞定位
Nucleus.
