FGF-2 Polyclonal Antibody
¥680.00
HSPB8/HSP22 Monoclonal Antibody(2C3)
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2601592
- 产品信息
商品描述
靶点-Target
HSPB8
反应性
Human,Rat,Mouse
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
2C3
免疫原
Recombinant Protein of HSPB8/HSP22
特异性
HSPB8/HSP22 protein detects endogenous levels of HSPB8/HSP22
基因名称
HSPB8
蛋白名称
Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Protein kinase H11) (Small stress protein-like protein HSP22)
别名
HSPB8;CRYAC;E2IG1;HSP22;PP1629;Heat shock protein beta-8;HspB8;Alpha-crystallin C chain;E2-induced gene 1 protein;Protein kinase H11;Small stress protein-like protein HSP22
Organism-1
Human
基因ID-1
26353
SwissProt-1
Q9UJY1
Organism-2
Mouse
SwissProt-2
Q9JK92
Organism-3
Rat
SwissProt-3
Q9EPX0
背景
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Translocates to nuclear foci during heat shock.
