GRP78/Bip Monoclonal Antibody(8G3)

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601584

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商品描述
  • 靶点-Target

    HSP A5/GRP78

  • 反应性

    Human,Rat

  • 应用

    WB,IHC,IF

  • 宿主物种-Host Species

    Mouse

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    78kD

  • 推荐稀释比

    WB 1:1000-2000;IHC 1:100-200;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Monoclonal

  • 克隆号

    8G3

  • 免疫原

    Synthetic Peptide of GRP78/Bip

  • 特异性

    GRP78/Bip protein detects endogenous levels of GRP78/Bip

  • 基因名称

    HSPA5

  • 蛋白名称

    78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)

  • 别名

    HSPA5;GRP78;78 kDa glucose-regulated protein;GRP-78;Endoplasmic reticulum lumenal Ca;2+;-binding protein grp78;Heat shock 70 kDa protein 5;Immunoglobulin heavy chain-binding protein;BiP

  • Organism-1

    Human

  • 基因ID-1

    3309

  • SwissProt-1

    P11021

  • Organism-2

    Mouse

  • SwissProt-2

    P20029

  • Organism-3

    Rat

  • SwissProt-3

    P06761

  • 背景

    The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010],

  • 细胞定位

    Endoplasmic reticulum lumen . Melanosome . Cytoplasm . Cell surface . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). Localizes to the cell surface of epithelial cells in response to high levels of free iron (PubMed:20484814, PubMed:24355926, PubMed:27159390). .