FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TNFA
反应性
Human,Rat,Mouse
应用
WB,IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
17,25kD
推荐稀释比
WB 1:1000-1:3000;IHC 1:50-1:200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
Q34
免疫原
Synthetic Peptide of TNF α
特异性
The antibody detects endogenous TNF α protein
基因名称
TNF TNFA TNFSF2
蛋白名称
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-doma
别名
Tumor necrosis factor;Cachectin;TNF-alpha;Tumor necrosis factor ligand superfamily member 2;TNF-a;[Cleaved into: Tumor necrosis factor, membrane form;N-terminal fragment;NTF;Intracellular domain 1;ICD1;Intracellular domain 2;ICD2;C-domain 1;C-domain 2;Tumor necrosis factor, soluble form]
Organism-1
Human
基因ID-1
7124
SwissProt-1
P01375
Organism-2
Mouse
SwissProt-2
P06804
Organism-3
Rat
SwissProt-3
P16599
背景
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type II membrane protein .; [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein.; [Tumor necrosis factor, soluble form]: Secreted .; [C-domain 1]: Secreted.; [C-domain 2]: Secreted.
