- 产品信息
商品描述
靶点-Target
MICU1
反应性
Human,Mouse,Rat
应用
WB,IF,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:1000-2000;IHC 1:100-200;IF 1:200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Recombinant Protein of MICU1
特异性
The antibody detects endogenous MICU1 protein.
基因名称
MICU1
蛋白名称
Calcium uptake protein 1, mitochondrial
别名
Calcium uptake protein 1, mitochondrial;Atopy-related autoantigen CALC;ara CALC;Calcium-binding atopy-related autoantigen 1;allergen Hom s 4
Organism-1
Human
基因ID-1
10367
SwissProt-1
Q9BPX6
Organism-2
Mouse
SwissProt-2
Q8VCX5
Organism-3
Rat
SwissProt-3
Q6P6Q9
背景
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013],
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein . Mitochondrion intermembrane space .





