- 产品信息
商品描述
靶点-Target
Actin_smooth muscle (SMA)
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:5000-50000;IHC 1:1000-2000
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
1E12
免疫原
Synthetic Peptide of α-SMA
特异性
The antibody detects endogenous α-SMA protein.
基因名称
ACTA2
蛋白名称
Actin, aortic smooth muscle
别名
ACTA2;ACTSA;ACTVS;GIG46;Actin, aortic smooth muscle;Alpha-actin-2;Cell growth-inhibiting gene 46 protein
Organism-1
Human
基因ID-1
59
SwissProt-1
P62736
Organism-2
Mouse
SwissProt-2
P62737
Organism-3
Rat
SwissProt-3
P62738
背景
The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008],
细胞定位
Cytoplasm, cytoskeleton.





