- 产品信息
商品描述
靶点-Target
JAK1
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
IHC1:50-200;WB 1:200-1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
3F12
免疫原
Synthesized peptide derived from human JAK1
特异性
This antibody detects endogenous levels of JAK1 at Human, Mouse,Rat
基因名称
JAK1 JAK1A JAK1B
蛋白名称
JAK1
别名
Tyrosine-protein kinase JAK1;Janus kinase 1;JAK-1;
Organism-1
Human
基因ID-1
3716
SwissProt-1
P23458
Organism-2
Mouse
SwissProt-2
P52332
背景
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
细胞定位
Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.





