FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Myd88
反应性
Human,Mouse,Rat
应用
IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
33kD
推荐稀释比
IHC 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
2H12
免疫原
Synthesized peptide derived from human Myd88
特异性
This antibody detects endogenous levels of Myd88 at Human, Mouse,Rat
基因名称
MYD88
蛋白名称
Myd88
别名
Myeloid differentiation primary response protein MyD88
Organism-1
Human
基因ID-1
4615
SwissProt-1
Q99836
Organism-2
Mouse
基因ID-2
17874
SwissProt-2
P22366
Organism-3
Rat
基因ID-3
301059
SwissProt-3
Q6Y1S1
背景
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
细胞定位
Cytoplasm . Nucleus .
