FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IκB β
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
45-48kD
推荐稀释比
IHC1:50-200;WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
3E4
免疫原
Synthesized peptide derived from human IκB β
特异性
This antibody detects endogenous levels of IκB β at Human, Mouse,Rat
基因名称
NFKBIB IKBB TRIP9
蛋白名称
IκB β
别名
NF-kappa-B inhibitor beta;NF-kappa-BIB;I-kappa-B-beta;IkB-B;IkB-beta;IkappaBbeta;Thyroid receptor-interacting protein 9;TR-interacting protein 9;TRIP-9;
Organism-1
Human
基因ID-1
4793
SwissProt-1
Q15653
Organism-2
Mouse
基因ID-2
18036
SwissProt-2
Q60778
Organism-3
Rat
SwissProt-3
Q9JIA3
背景
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011],
细胞定位
Cytoplasm . Nucleus .
