P27 Kip1 Mouse mAb(1A7)

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601523

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商品描述
  • 靶点-Target

    P27 Kip1

  • 反应性

    Human,Mouse,Rat

  • 应用

    IHC,WB

  • 宿主物种-Host Species

    Mouse

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    27kD

  • 推荐稀释比

    IHC1:50-200;WB 1:1000-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Monoclonal

  • 克隆号

    1A7

  • 免疫原

    Synthesized peptide derived from human P27 Kip1

  • 特异性

    This antibody detects endogenous levels of P27 Kip1 at Human, Mouse,Rat

  • 基因名称

    P27 Kip1

  • 蛋白名称

    P27 Kip1

  • Organism-1

    Human

  • SwissProt-1

    P45627

  • 背景

    Cyclin dependent kinase inhibitor 1B(CDKN1B) Homo sapiens This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.