- 产品信息
商品描述
靶点-Target
NOS3
反应性
Human,Mouse,Rat,Rabbit
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
130-140kD
推荐稀释比
WB 1:500-2000
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Recombinant Protein of eNOS
特异性
The antibody detects endogenous eNOS protein.
基因名称
NOS3
蛋白名称
Nitric oxide synthase, endothelial
别名
NOS3;Nitric oxide synthase, endothelial;Constitutive NOS;cNOS;EC-NOS;Endothelial NOS;eNOS;NOS type III;NOSIII
Organism-1
Human
基因ID-1
4846
SwissProt-1
P29474
Organism-2
Mouse
基因ID-2
18127
SwissProt-2
P70313
Organism-3
Rat
基因ID-3
24600
SwissProt-3
Q62600
背景
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
细胞定位
Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.





