α skeletal muscle actin Monoclonal Antibody(4B11)

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601483

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商品描述
  • 靶点-Target

    Actin skeletal muscle α

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,IP

  • 宿主物种-Host Species

    Mouse

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    42kD

  • 推荐稀释比

    WB 1:500-10000;IP 1:200;IF 1:200;IHC 1:50-300

  • 组成

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

  • 纯化工艺

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    4B11

  • 免疫原

    Synthetic Peptide of α skeletal muscle actin

  • 特异性

    The antibody detects endogenous α Skeletal Muscle Actin protein.

  • 基因名称

    ACTA1

  • 蛋白名称

    Actin alpha skeletal muscle

  • 别名

    ACTA1;ACTA;Actin, alpha skeletal muscle;Alpha-actin-1

  • Organism-1

    Human

  • 基因ID-1

    58

  • SwissProt-1

    P68133

  • Organism-2

    Mouse

  • 基因ID-2

    11459

  • SwissProt-2

    P68134

  • Organism-3

    Rat

  • 基因ID-3

    29437

  • SwissProt-3

    P68136

  • 背景

    The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasm, cytoskeleton.