FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PARP
反应性
Human,Chicken(testedbyourcustomer）
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
116kD
推荐稀释比
WB 1:1000-3000
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
M3
免疫原
Synthetic Peptide of PARP
特异性
The antibody detects endogenous PARP protein.
基因名称
PARP1
蛋白名称
Poly [ADP-ribose] polymerase 1
别名
Poly [ADP-ribose] polymerase 1;PARP-1;ADP-ribosyltransferase diphtheria toxin-like 1;ARTD1;NAD;+;ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1;
Organism-1
Human
基因ID-1
142
SwissProt-1
P09874
Organism-2
Mouse
SwissProt-2
P11103
Organism-3
Rat
基因ID-3
25591
SwissProt-3
P27008
背景
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of DNA damage. .
