NF-κB p65 (PTR2315) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601466

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商品描述
  • 靶点-Target

    NFkB p65

  • 反应性

    Human,Mouse,

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2a,Kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    65kD

  • MW(Observed)

    70kD

  • 推荐稀释比

    WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    Protein G

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PTR2315

  • 免疫原

    Recombinant Protein of human Transcription factor p65 AA range: 200-300

  • 特异性

    This antibody detects endogenous levels of NF-κB p65 protein.

  • 基因名称

    RELA

  • 蛋白名称

    Transcription factor p65

  • 别名

    RELA;NFKB3;Transcription factor p65;Nuclear factor NF-kappa-B p65 subunit;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

  • Organism-1

    Human

  • 基因ID-1

    5970

  • SwissProt-1

    Q04206

  • Organism-2

    Mouse

  • 基因ID-2

    19697

  • SwissProt-2

    Q04207

  • 背景

    NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],