- 产品信息
商品描述
靶点-Target
CD25
反应性
Human
应用
IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
31kD
推荐稀释比
IHC 1:200;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
Q22
免疫原
Synthetic Peptide of CD25
特异性
The antibody detects endogenous human CD25 protein.
基因名称
IL2RA
蛋白名称
Interleukin-2 receptor subunit alpha
别名
IL2RA;Interleukin-2 receptor subunit alpha;IL-2 receptor subunit alpha;IL-2-RA;IL-2R subunit alpha;IL2-RA;TAC antigen;p55;CD25
Organism-1
Human
基因ID-1
3559
SwissProt-1
P01589
Organism-2
Mouse
基因ID-2
16184
SwissProt-2
P01590
Organism-3
Rat
基因ID-3
25704
SwissProt-3
P26897
背景
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009],
细胞定位
Membrane; Single-pass type I membrane protein.





