- 产品信息
商品描述
靶点-Target
CD41
反应性
Human
应用
IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
113kD
推荐稀释比
IHC 1:100;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
Q90
免疫原
Synthetic Peptide of CD41
特异性
The antibody detects endogenous human CD41/ Intergrin α2b protein.
基因名称
ITGA2B
蛋白名称
Integrin alpha-IIb
别名
ITGA2B;GP2B;ITGAB;Integrin alpha-IIb;GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD41
Organism-1
Human
基因ID-1
3674
SwissProt-1
P08514
Organism-2
Mouse
基因ID-2
16399
SwissProt-2
Q9QUM0
背景
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],
细胞定位
Membrane; Single-pass type I membrane protein.





