FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CD16
反应性
Human
应用
WB,IHC,IF,
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:1000;IHC 1:50-300;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
Q32
免疫原
Synthetic Peptide of CD16
特异性
The antibody detects endogenous CD16 protein.
基因名称
FCGR3A/FCGR3B
蛋白名称
Low affinity immunoglobulin gamma Fc region receptor III-A/Low affinity immunoglobulin gamma Fc region receptor III-B
Organism-1
Human
基因ID-1
2214;2215
SwissProt-1
P08637;O75015
背景
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq,
细胞定位
Cell membrane ; Single-pass type I membrane protein . Secreted . Exists also as a soluble receptor. .
