FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
XRCC4
反应性
Human
应用
WB,IHC,IF,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:2000;IP 1:200;IF 1:200;IHC 1:50-300
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
5C10
免疫原
Synthetic Peptide of XRCC4
特异性
The antibody detects endogenous XRCC4 proteins.
基因名称
XRCC4
蛋白名称
DNA repair protein XRCC4
别名
XRCC4;DNA repair protein XRCC4;X-ray repair cross-complementing protein 4
Organism-1
Human
基因ID-1
7518
SwissProt-1
Q13426
Organism-2
Mouse
基因ID-2
108138
SwissProt-2
Q924T3
背景
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015],
细胞定位
Nucleus . Chromosome . Localizes to site of double-strand breaks. .; [Protein XRCC4, C-terminus]: Cytoplasm . Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3). .
