FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CD10
反应性
Human,Mouse,Rat
应用
IF,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
86kD
推荐稀释比
IF 1:50-200;IHC 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
5B8
免疫原
Synthetic Peptide of CD10
特异性
The antibody detects endogenous CD10 proteins.
基因名称
MME
蛋白名称
Neprilysin
别名
MME;EPN;Neprilysin;Atriopeptidase;Common acute lymphocytic leukemia antigen;CALLA;Enkephalinase;Neutral endopeptidase 24.11;NEP;Neutral endopeptidase;Skin fibroblast elastase;SFE;CD10
Organism-1
Human
基因ID-1
4311
SwissProt-1
P08473
Organism-2
Mouse
基因ID-2
17380
SwissProt-2
Q61391
Organism-3
Rat
基因ID-3
24590
SwissProt-3
P07861
背景
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this
细胞定位
Cell membrane; Single-pass type II membrane protein.
