FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Kif 7
反应性
Human,Mouse,Rat
应用
IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
推荐稀释比
IHC 1:50-200;IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
3F8
免疫原
Synthetic Peptide of Kif 7
特异性
The antibody detects endogenous Kif 7 proteins.
基因名称
KIF7
蛋白名称
Kinesin-like protein KIF7
别名
Kinesin-like protein KIF7
Organism-1
Human
基因ID-1
374654
SwissProt-1
Q2M1P5
Organism-2
Mouse
基因ID-2
16576
SwissProt-2
B7ZNG0
背景
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011],
细胞定位
Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Localizes to the cilium tip.
