- 产品信息
商品描述
靶点-Target
Cytokeratin 19
反应性
Human,Mouse,Rat
应用
IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
44kD
推荐稀释比
IHC 1:200-400;IF/ICC1:200-400
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
11F5
免疫原
Synthetic Peptide of CK19
特异性
The antibody detects endogenous CK19 proteins.
基因名称
KRT19
蛋白名称
Keratin type I cytoskeletal 19
别名
KRT19;Keratin, type I cytoskeletal 19;Cytokeratin-19;CK-19;Keratin-19;K19
Organism-1
Human
基因ID-1
3880
SwissProt-1
P08727
Organism-2
Mouse
基因ID-2
16669
SwissProt-2
P19001
Organism-3
Rat
基因ID-3
360626
SwissProt-3
Q63279
背景
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008],
细胞定位
intermediate filament,plasma membrane,dystrophin-associated glycoprotein complex,Z disc,sarcolemma,costamere,extracellular exosome,cell periphery,terminal web,





