FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AMACR
反应性
Human,Mouse,Rat
应用
WB,IF,IHC
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:1000;IHC 1:200;IF 1:200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
4A12
免疫原
Synthetic Peptide of AMACR
特异性
The antibody detects endogenous AMCAR/P504S proteins.
基因名称
AMACR
蛋白名称
Alpha-methylacyl-CoA racemase
别名
AMACR;Alpha-methylacyl-CoA racemase;2-methylacyl-CoA racemase
Organism-1
Human
基因ID-1
23600
SwissProt-1
Q9UHK6
Organism-2
Mouse
基因ID-2
17117
SwissProt-2
O09174
Organism-3
Rat
SwissProt-3
P70473
背景
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011],
细胞定位
Peroxisome . Mitochondrion .
