- 产品信息
商品描述
靶点-Target
HSP70
反应性
Human,Mouse,Rat
应用
WB,IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:1000-2000;IF 1:100-200;IHC 1:50-300
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
3G10
免疫原
Human protein HSP70 at C-terminal
特异性
The antibody detects endogenous HSP70 proteins.
基因名称
HSPA1A;HSPA1B
蛋白名称
Heat shock 70 kDa protein 1A/1B
别名
HSPA1A;HSPA1;HSPA1B;Heat shock 70 kDa protein 1A/1B;Heat shock 70 kDa protein 1/2;HSP70-1/HSP70-2;HSP70.1/HSP70.2
Organism-1
Human
基因ID-1
3303;3304
SwissProt-1
P0DMV8;P0DMV9
背景
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Secreted . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.





