- 产品信息
商品描述
靶点-Target
Tubulin α
反应性
Human,Mouse,Rat,
应用
IHC,WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG2b,Kappa
修饰-Modification
Unmodified
MW(Calculated)
52kD
MW(Observed)
52kD
推荐稀释比
IHC 1:200-1000;WB 1:1000-5000;IF 1:100-500;ELISA 1:5000-50000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
克隆号
PT2182
免疫原
Recombinant Protein of Tubulin alpha-1A chain. AA range: 350-451
特异性
This antibody detects endogenous levels of Tubulin α protein.
基因名称
TUBA1A
蛋白名称
Tubulin alpha-1A chain
Organism-1
Human
基因ID-1
7846;10376
SwissProt-1
Q71U36;P68363;Q9BQE3;P0DPH7;P0DPH8;Q6PEY2;P68366;Q9NY65
Organism-2
Mouse
基因ID-2
22142;22143
Organism-3
Rat
基因ID-3
64158;500929
SwissProt-3
P68370;Q6P9V9
背景
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
细胞定位
Cytoplasmic





