COX IV (PTR1399) mouse mAb

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2601410

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商品描述
  • 靶点-Target

    COX IV

  • 反应性

    Human,Mouse,Rat,

  • 应用

    WB,IF,ELISA,IHC

  • 宿主物种-Host Species

    Mouse

  • 同种型-Isotype

    IgG2b,kappa

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    20kD

  • MW(Observed)

    17kD

  • 推荐稀释比

    IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000;

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 克隆号

    PTR1399

  • 免疫原

    AA range: 100-200

  • 特异性

    This antibody detects endogenous levels of COX IV protein.

  • 基因名称

    COX4I1

  • 蛋白名称

    Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

  • 别名

    COX4I1;COX4;Cytochrome c oxidase subunit 4 isoform 1, mitochondrial;Cytochrome c oxidase polypeptide IV;Cytochrome c oxidase subunit IV isoform 1;COX IV-1

  • Organism-1

    Human

  • 基因ID-1

    1327

  • SwissProt-1

    P13073

  • Organism-2

    Mouse

  • 基因ID-2

    12857

  • SwissProt-2

    P19783

  • Organism-3

    Rat

  • 基因ID-3

    29445

  • SwissProt-3

    P10888

  • 背景

    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes

  • 细胞定位

    Mitochondrion inner membrane