FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GAPDH
反应性
Human,Rat,Mouse,Mk,Dg,Ch,Hamster,Rabbit,Pig,sheep,Insect,Yeast
应用
WB,IF,IHC
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1
偶联-Conjugate
Biotin
修饰-Modification
Unmodified
推荐稀释比
Optimal working dilutions should be determined experimentally by the investigator;Suggested starting dilutions are as follows:WB 1:5000;IHC 1:200.
组成
Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
浓度
1mg/ml
克隆性
Monoclonal
克隆号
2B8
特异性
GAPDH Monoclonal Antibody(2B8) Biotin conjugated specially designed for your WB or IHC analysis.
基因名称
GAPDH
蛋白名称
Glyceraldehyde-3-phosphate dehydrogenase
别名
GAPDH
Organism-1
Human
基因ID-1
2597
SwissProt-1
P04406
背景
glyceraldehyde-3-phosphate dehydrogenase(GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri
细胞定位
Cytoplasm, cytosol . Nucleus . Cytoplasm, perinuclear region . Membrane . Cytoplasm, cytoskeleton . Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions (PubMed:12829261). .
