- 产品信息
商品描述
靶点-Target
COX IV
反应性
Human,Rat,Mouse
应用
WB,IHC,IF,
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1
偶联-Conjugate
Biotin
修饰-Modification
Unmodified
推荐稀释比
Optimal working dilutions should be determined experimentally by the investigator;Suggested starting dilutions are as follows:WB 1:1000-3000;IHC 1:50-300.
组成
Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
浓度
1mg/ml
克隆性
Monoclonal
克隆号
6C8
特异性
COX IV Monoclonal Antibody(6C8) Biotin conjugated specially designed for your WB or IHC analysis.
基因名称
COX4I1
蛋白名称
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
别名
COX4I1
Organism-1
Human
基因ID-1
1327
SwissProt-1
P13073
背景
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein .





