- 产品信息
商品描述
靶点-Target
COX IV
反应性
Human,Rat,Mouse
应用
WB,IHC,IF,
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1
偶联-Conjugate
AbFluor 647
修饰-Modification
Unmodified
推荐稀释比
Optimal working dilutions should be determined experimentally by the investigator;Suggested starting dilutions are as follows:IHC 1:50-300;IF 1:200 .
组成
Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
浓度
1mg/ml
克隆性
Monoclonal
克隆号
6C8
特异性
COX IV Monoclonal Antibody(6C8) AbFluor™ 647 Conjugated specially designed for your Immunofluorescence analysis.
基因名称
COX4I1
蛋白名称
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
别名
COX4I1
Organism-1
Human
基因ID-1
1327
SwissProt-1
P13073
背景
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein .





