FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Toll-like Receptor 7
反应性
Transfected
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
121kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Toll-like Receptor protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Toll-like Receptor and does not cross-react with related proteins.
基因名称
tlr7
别名
PRO285;TLR 7;Tlr7;TLR7_HUMAN;Toll like receptor 7;Toll-like receptor 7;UNQ248.
Organism-1
Human
基因ID-1
51284
SwissProt-1
Q9NYK1
Organism-2
Mouse
SwissProt-2
P58681
背景
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endosome . Lysosome . Cytoplasmic vesicle, phagosome . Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. .
