FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Wnt3
反应性
Transfected
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Wnt3 protein fragments expressed in E.coli.
特异性
Transfected Only.
基因名称
wnt3
别名
Int 4;INT4;MGC131950;MGC138321;MGC138323;Proto-oncogene Int-4 homolog;Proto-oncogene Wnt-3;wingless type MMTV integration site family member 3;Wnt 3 proto oncogene protein;WNT 3 proto oncogene protein precursor;wnt3;WNT3_HUMAN.
Organism-1
Human
基因ID-1
7473
SwissProt-1
P56703
Organism-2
Mouse
SwissProt-2
P17553
背景
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008],
细胞定位
Secreted, extracellular space, extracellular matrix . Secreted .
