FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MKK3/6
反应性
Human,Rat
应用
WB,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human MKK6 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of MKK3 and MKK6 and does not cross-react with related proteins.
基因名称
map2k3
别名
AW212142;dual specificity mitogen activated protein kinase kinase 3;Dual specificity mitogen activated protein kinase kinase 6;Dual specificity mitogen-activated protein kinase kinase 3;MAP kinase kinase 3;MAP kinase kinase 6;map2k3;MAP2K6;MAPK ERK kinase 3;MAPK/ERK kinase 3;MAPK/ERK kinase 6;MAPKK 3;MAPKK 6;MAPKK3;MAPKK6;MEK 3;MEK 6;MEK3;Mitogen activated protein kinase kinase 3;Mitogen activated protein kinase kinase 6;MKK 3;MKK3;MKK6;mMKK3b;MP2K3_HUMAN;PRKMK 3;PRKMK3;PRKMK6;Protein kinase, mitogen activated, kinase 6;MAP kinase kinase 6;protein kinase, mitogen-activated, kinase 3;SAPK kinase 2;SAPKK 2;SAPKK 3;SAPKK-2;SAPKK2;SAPKK3;Stress activated protein kinase kinase 2;Stress activated protein kinase kinase 3;Stress-activated protein kinase kinase 2.
Organism-1
Human
基因ID-1
5608
SwissProt-1
P52564
Organism-2
Mouse
SwissProt-2
P70236
背景
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Binds to microtubules.
