- 产品信息
商品描述
靶点-Target
GRAP2
反应性
Human
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Recombinant protein of human GRAP2.
特异性
This antibody detects endogenous levels of GRAP2 and does not cross-react with related proteins.
基因名称
grap2
别名
Adapter protein GRID;GADS;GADS protein;GRAP-2;Grap2;GRAP2_HUMAN;GRB-2-like protein;GRB2-related adapter protein 2;GRB2-related adaptor protein 2;GRB2-related protein with insert domain;GRB2L;GRBLG;GRBX;Grf-40;Grf40 adapter protein;Grf40;GRID;Growth factor receptor-binding protein;Growth factor receptor-bound protein 2-related adaptor protein 2;GRPL;Hema;Hematopoietic cell-associated adapter protein GrpL;Hematopoietic cell-associated adaptor protein GRPL;Mona;p38;Protein GADS;SH3-SH2-SH3 adapter Mona;SH3-SH2-SH3 adaptor molecule.
Organism-1
Human
基因ID-1
9402
SwissProt-1
O75791
Organism-2
Mouse
SwissProt-2
O89100
背景
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014],
细胞定位
Nucleus . Cytoplasm . Endosome .





