FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NGAL
反应性
Human
应用
ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
23kD
推荐稀释比
ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Recombinant protein of human NGAL.
基因名称
LCN2 HNL NGAL
别名
24p3;25 kDa alpha-2-microglobulin-related subunit of MMP-9;HNL;Lcn2;Lipocalin 2;Lipocalin-2;Migration stimulating factor inhibitor;MSFI;Neutrophil gelatinase-associated lipocalin;NGAL;NGAL_HUMAN;Oncogene 24p3;p25;Siderocalin.
Organism-1
Human
基因ID-1
3934
SwissProt-1
P80188
Organism-2
Mouse
SwissProt-2
P11672
背景
This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015],
细胞定位
Secreted . Cytoplasmic granule lumen . Cytoplasmic vesicle lumen . Upon binding to the SLC22A17 (24p3R) receptor, it is internalized (By similarity). Releases the bound iron in the acidic lumen of cytoplasmic vesicles (PubMed:12453413, PubMed:20581821). .
