- 产品信息
商品描述
靶点-Target
Vimentin
反应性
Human
应用
WB,IF,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:1000;ICC 1:800;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Vimentin protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Vimentin and does not cross-react with related proteins.
基因名称
vim
别名
CTRCT30;Epididymis luminal protein 113;FLJ36605;HEL113;OTTHUMP00000019224;VIM;VIME_HUMAN;Vimentin.
Organism-1
Human
基因ID-1
7431
SwissProt-1
P08670
Organism-2
Mouse
SwissProt-2
P20152
背景
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Nucleus matrix . Cell membrane .





