- 产品信息
商品描述
靶点-Target
Leptin
反应性
Human
应用
ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
16kD
推荐稀释比
ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant full length of human Leptin protein expressed in E.coli.
特异性
This antibody detects human Leptin proteins.
基因名称
lep
别名
FLJ94114;LEP;LEP_HUMAN;LEPD;Leptin;murine obesity homolog;Leptin;obesity homolog, mouse;Leptin;Leptin Murine Obesity Homolog;Leptin Precursor Obesity Factor;OB;Obese Protein;Obese, mouse, homolog of;Obesity;Obesity factor;Obesity factor;Obesity homolog mouse;Obesity Murine Homolog Leptin;OBS;OTTHUMP00000212285.
Organism-1
Human
基因ID-1
3952
SwissProt-1
P41159
Organism-2
Mouse
SwissProt-2
P41160
背景
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008],
细胞定位
Secreted .





