- 产品信息
商品描述
靶点-Target
RBBP5
反应性
Human,Mouse,Rat
应用
WB,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:1000;ICC 1:100;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human RBBP5 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of RBBP5 and does not cross-react with related proteins.
基因名称
rbbp5
别名
RBBP 5;RBBP-5;RBBP5;RBBP5_HUMAN;RBQ 3;RBQ3;Retinoblastoma binding protein 5;Retinoblastoma binding protein RBQ3;Retinoblastoma binding protein5;Retinoblastoma-binding protein 5;Retinoblastoma-binding protein RBQ-3;SWD1;SWD1, Set1c WD40 repeat protein, homolog.
Organism-1
Human
基因ID-1
5929
SwissProt-1
Q15291
Organism-2
Mouse
SwissProt-2
Q8BX09
背景
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010],
细胞定位
Nucleus .





