FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Histone H2A.X
反应性
Human,Mouse
应用
WB,IHC,IF
宿主物种-Host Species
Mouse
修饰-Modification
Phospho
MW(Observed)
15kD
推荐稀释比
WB 1:2000;IHC 1:200-400;ICC 1:400;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2A.X.
特异性
This antibody detects endogenous levels of H2A.X only when phosphorylated at serine 139.
基因名称
H2AFX
蛋白名称
Histone H2A.x,γH2AX
别名
H2A histone family, member X;H2A.X;H2a/x;H2AFX;H2AX;H2AX histone;H2AX_HUMAN;Histone H2A.X;Histone H2AX
Organism-1
Human
基因ID-1
3014
SwissProt-1
P16104
Organism-2
Mouse
SwissProt-2
P27661
背景
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],
细胞定位
Nucleus . Chromosome .
