FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Human IgM
反应性
Human
应用
ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
75kD
推荐稀释比
ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant full length of human IgM heavy chain protein expressed in E.coli.
特异性
This antibody detects human IgM proteins.
基因名称
igm
别名
AGM1;Constant region of heavy chain of IgM;DKFZp686I15196;DKFZp686I15212;FLJ00385;Ig mu chain C region;IGHM;Immunoglobin heavy constant mu;Immunoglobulin mu;MGC104996;MGC52291;MU;VH.
Organism-1
Human
基因ID-1
3507
SwissProt-1
P01871
Organism-2
Mouse
SwissProt-2
P01872
背景
Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains (see MIM 147200) joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070), joining (J) genes (see MIM 147010), and diversity (D) genes (see MIM 146910). The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which d
细胞定位
[Isoform 1]: Secreted. During differentiation, B-lymphocytes switch from expression of membrane-bound IgM to secretion of IgM.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.
