FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GADD45α
反应性
Transfected
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human GADD45 α protein expressed in E.coli
特异性
Transfected Only.
基因名称
gadd45a
别名
DDIT 1;DDIT-1;DDIT1;DNA damage inducible transcript 1;DNA damage-inducible transcript 1 protein;GA45A_HUMAN;GADD45;GADD45A;Growth arrest and DNA damage inducible 45 alpha;Growth arrest and DNA damage inducible alpha;Growth arrest and DNA damage-inducible protein GADD45 alpha.
Organism-1
Human
基因ID-1
1647
SwissProt-1
P24522
Organism-2
Mouse
SwissProt-2
P48316
背景
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010],
细胞定位
Nucleus .
