- 产品信息
商品描述
靶点-Target
Hsp60
反应性
Human,Mouse,Rat
应用
WB,IF,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:1000;ICC 1:100;IP 1:100;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Hsp60 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Hsp60 and does not cross-react with related proteins.
基因名称
hsp60
别名
60 kDa chaperonin;60 kDa heat shock protein mitochondrial;60 kDa heat shock protein, mitochondrial;CH60_HUMAN;Chaperonin 60;Chaperonin;Chaperonin, 60-KD;CPN 60;CPN60;fa04a05;GROEL;GroEL Homolog;Heat shock 60kD protein 1 chaperonin;Heat shock 60kDa protein 1;Heat shock protein 1;chaperonin;Heat Shock Protein 60;Heat shock protein 65;HLD4;Hsp 60;HSP 65;HSP-60;HSP60;HSP65;HSPD 1;HSPD1;HuCHA60;Mitochondrial matrix protein P1;P60 lymphocyte protein;Short heat shock protein 60 Hsp60s1;Spastic paraplegia 13;SPG 13;SPG13.
Organism-1
Human
基因ID-1
3329
SwissProt-1
P10809
Organism-2
Mouse
SwissProt-2
P63038
背景
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010],
细胞定位
Mitochondrion matrix.





