FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
XRCC1
反应性
Human
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
82kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human XRCC1 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of XRCC1 and does not cross-react with related proteins.
基因名称
xrcc1
别名
DNA repair protein XRCC1;RCC;X ray repair complementing defective repair in chinese hamster;X ray repair complementing defective repair in chinese hamster cells 1;X ray Repair Complementing Defective Repair in Chinese Hamster Cells;X ray repair cross complementing protein 1;X ray repair, complementing defective, repair in Chinese hamster;X-ray repair cross-complementing protein 1;XRCC 1;Xrcc1;XRCC1_HUMAN.
Organism-1
Human
基因ID-1
7515
SwissProt-1
P18887
Organism-2
Mouse
SwissProt-2
Q60596
背景
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Moves from the nucleoli to the global nuclear chromatin upon DNA damage. .
