- 产品信息
商品描述
靶点-Target
Keratin(50-60kDa)
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
62kD
推荐稀释比
WB 1:2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human KRT5 beta protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Keratin(50-60kDa) proteins.
基因名称
krt5
别名
58 kDa cytokeratin;CK 5;CK-5;CK5;Cytokeratin-5;Cytokeratin5;DDD;DDD1;EBS 2;EBS2;epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types;K2C5_HUMAN;K5;Keratin 5;epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types;keratin 5;epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types;Keratin 5;Keratin;keratin complex 2, basic, gene 5;Keratin Type II Cytoskeletal 5;keratin, type II cytoskeletal 5;Keratin-5;Keratin5;KRT 5;KRT 5A;KRT5;KRT5A;type II cytoskeletal 5;Type-II keratin Kb5.
Organism-1
Human
基因ID-1
3852
SwissProt-1
P13647
Organism-2
Mouse
SwissProt-2
Q922U2
背景
keratin 5(KRT5) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],
细胞定位
nucleus,cytoplasm,mitochondrion,cytosol,intermediate filament,plasma membrane,membrane,keratin filament,extracellular exosome,





