FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Ku-80
反应性
Human,Monkey
应用
WB,IF,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
86kD
推荐稀释比
WB 1:1000;ICC 1:400;IP 1:100;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Ku80 protein fragments expressed in E.coli
特异性
This antibody detects endogenous levels of Ku80 and does not cross-react with related proteins.
基因名称
xrcc5
别名
ATP dependent DNA helicase II 80 kDa subunit;ATP dependent DNA helicase II 86 Kd subunit;ATP dependent DNA helicase II;ATP-dependent DNA helicase 2 subunit 2;ATP-dependent DNA helicase II 80 kDa subunit;CTC box binding factor 85 kDa;CTC box-binding factor 85 kDa subunit;CTC85;CTCBF;DNA repair protein XRCC5;Double strand break rejoining;FLJ39089;G22P2;KARP 1;KARP1;Ku 80;Ku autoantigen 80kDa;Ku80;Ku86;Ku86 autoantigen related protein 1;KUB 2;KUB2;Lupus Ku autoantigen protein p86;NFIV;Nuclear factor IV;Thyroid lupus autoantigen;Thyroid-lupus autoantigen;TLAA;X ray repair complementing defective repair in Chinese hamster cells 5;double strand break rejoining;X-ray repair complementing defective repair in Chinese hamster cells 5;double-strand-break rejoining;X-ray repair cross-complementing protein 5;Xray repair complementing defective repair in Chinese hamster cells 5;XRCC 5;XRCC5;XRCC5_HUMAN.
Organism-1
Human
基因ID-1
7520
SwissProt-1
P13010
Organism-2
Mouse
SwissProt-2
P27641
背景
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus, nucleolus . Chromosome .
