FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HSP90B
反应性
Human,Mouse,Rat,Monkey,Hamster
应用
WB,ICC,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
90kD
推荐稀释比
WB 1:2000;ICC 1:200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Hsp90 beta protein fragments expressed in E.coli
特异性
This antibody detects endogenous levels of Hsp90 beta and does not cross-react with Hsp90 alpha and other proteins.
基因名称
hsp90ab1
别名
HSP90AB1;90 kda heat shock protein beta HSP90 beta;D6S182;FLJ26984;Heat shock 84 kDa;Heat shock 90kD protein 1, beta;Heat shock 90kDa protein 1 beta;Heat shock protein 90kDa alpha;cytosolic;class B member 1;Heat shock protein beta;Heat shock protein HSP 90 beta;Heat shock protein HSP 90-beta;HS90B_HUMAN;HSP 84;HSP 90;HSP 90 b;HSP 90b;HSP84;HSP90 BETA;hsp90ab1;HSP90B;HSPC2;HSPCB.
Organism-1
Human
基因ID-1
3326
SwissProt-1
P08238
Organism-2
Mouse
SwissProt-2
P11499
背景
This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012],
细胞定位
Cytoplasm . Melanosome . Nucleus . Secreted . Cell membrane . Dynein axonemal particle . Cell surface . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Translocates with BIRC2 from the nucleus to the cytoplasm during differentiation (PubMed:18239673). Secreted when associated with TGFB1 processed form (LAP) (PubMed:20599762). .
