- 产品信息
商品描述
靶点-Target
CD31
反应性
Human
应用
WB,IP
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human CD31 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of CD31 and does not cross-react with related proteins.
基因名称
pecam1
别名
Adhesion molecule;CD31;CD31 antigen;CD31 EndoCAM;Endocam;FLJ34100;FLJ58394;GPIIA;GPIIA';PECA1;PECA1_HUMAN;Pecam 1;PECAM 1 CD31 EndoCAM;PECAM;PECAM-1;Pecam1;Platelet endothelial cell adhesion molecule;Platelet/endothelial cell adhesion molecule 1;Platelet/endothelial cell adhesion molecule.
Organism-1
Human
基因ID-1
18613
SwissProt-1
P16284
Organism-2
Mouse
SwissProt-2
Q08481
背景
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell surface expression on neutrophils is down-regulated upon fMLP or CXCL8/IL8-mediated stimulation. .; [Isoform Long]: Cell membrane ; Single-pass type I membrane protein . Membrane raft . Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells. .; [Isoform Delta15]: Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells.





