FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FAK
反应性
Human
应用
WB,IF
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
125kD
推荐稀释比
WB 1:1000;ICC 1:200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human FAK protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of FAK and does not cross-react with related proteins.
基因名称
ptk2
别名
FADK 1;FADK;FAK 1;FAK 1;FAK related non kinase polypeptide;FAK1;FAK1_HUMAN;Focal adhesion kinase 1;Focal adhesion kinase 1;Focal adhesion Kinase;Focal adhesion kinase isoform FAK Del33;Focal adhesion kinase related nonkinase;FRNK;p125FAK;pp125FAK;pp125FAK;PPP1R71;Protein phosphatase 1 regulatory subunit 71;Protein tyrosine kinase 2;Protein Tyrosine Kinase Cytoplasmic;Protein Tyrosine Kinase Cytoplasmic;Protein-tyrosine kinase 2;PTK 2;PTK 2;PTK2;PTK2 protein tyrosine kinase 2;PTK2 protein tyrosine kinase 2.
Organism-1
Human
基因ID-1
5747
SwissProt-1
Q05397
Organism-2
Mouse
SwissProt-2
P34152
背景
protein tyrosine kinase 2(PTK2) Homo sapiens This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015],
细胞定位
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus. Cytoplasm, cytoskeleton, cilium basal body . Constituent of focal adhesions. Detected at microtubules.
