FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ALDH2
反应性
Human,Mouse,Rat,Monkey,Hamster
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
56kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human ALDH2 protein fragments expressed in E.coli
特异性
This antibody detects endogenous levels of ALDH2 and does not cross-react with related proteins.
基因名称
aldh2
别名
Acetaldehyde dehydrogenase 2;Aldehyde dehydrogenase 2 family;mitochondrial;Aldehyde dehydrogenase 2 family;Aldehyde dehydrogenase mitochondrial;Aldehyde dehydrogenase, mitochondrial;ALDH 2;ALDH class 2;ALDH E2;ALDH-E2;Aldh2;ALDH2_HUMAN;ALDHI;ALDM;Liver mitochondrial ALDH;MGC1806;Mitochondrial aldehyde dehydrogenase 2;MS767;Nucleus encoded mitochondrial aldehyde dehydrogenase 2.
Organism-1
Human
基因ID-1
217
SwissProt-1
P05091
Organism-2
Mouse
SwissProt-2
P47738
背景
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform,
细胞定位
Mitochondrion matrix.
