FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IL18BP
反应性
Human
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
37kD
推荐稀释比
WB 1:400
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human IL18 binding protein protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of IL18 binding protein and does not cross-react with related proteins.
基因名称
il18bp
别名
I18BP_HUMAN;IL-18BP;IL18 BP;IL18 BPa;IL18BP;IL18BPa;Interleukin 18 binding protein;Interleukin-18-binding protein;MC51L 53L 54L homolog gene product;Tadekinig alfa;Tadekinig-alfa.
Organism-1
Human
基因ID-1
10068
SwissProt-1
O95998
Organism-2
Mouse
SwissProt-2
Q9Z0M9
背景
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011],
细胞定位
Secreted .
