FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Annexin VI
反应性
Human
应用
WB
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
76kD
推荐稀释比
WB 1:1000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant human Annexin VI protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of Annexin VI and does not cross-react with related proteins.
基因名称
anxa6
别名
67 kDa calelectrin;Annexin A6;Annexin VI;Annexin VI p68;Annexin-6;AnnexinA6;AnnexinVI;ANX 6;ANX A6;ANX6;ANXA6;ANXA6_HUMAN;Calcium binding protein p68;Calelectrin;Calphobindin II;Calphobindin-II;CalphobindinII;CBP 68;Chromobindin 20;CPBII;Lipocortin VI;LipocortinVI;Protein III;ProteinIII.
Organism-1
Human
基因ID-1
309
SwissProt-1
P08133
Organism-2
Mouse
SwissProt-2
P14824
背景
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010],
细胞定位
Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
